Supply High Quality Pure Nitazoxanide CAS 55981-09-4
Product Description
Product Name |
Supply High Quality Pure Nitazoxanide CAS 55981-09-4 |
Appearance |
White powder |
Molecular formula |
C12H9N3O5S |
Molecular weight |
307.28 |
Keywords |
Powder Nitazoxanide,Price Nitazoxanide; Pure Nitazoxanide |
Shelf Life |
24 months when properly stored |
Storage |
Keep in a cool, dry, dark location |
Function
What is Nitazoxanide?
Nitazoxanide is a synthetic nitrothiazolyl-salicylamide derivative and an antiprotozoal agent. (IC50 for canine influenza virus ranges from 0.17 to 0.21 μM).Target: OthersNitazoxanide is a synthetic nitrothiazolyl-salicylamide derivative and an antiprotozoal agent. In vitro studies demonstrated much broader activity. Dr. Rossignol co-founded Romark Laboratories, with the goal of bringing nitazoxanide to market as an anti-parasitic drug. Initial studies in the USA were conducted in collaboration with Unimed Pharmaceuticals, Inc. (Marietta, GA) and focused on development of the drug for treatment of cryptosporidiosis in AIDS.The anti-protozoal activity of nitazoxanide is believed to be due to interference with the pyruvate:ferredoxin oxidoreductase (PFOR) enzyme dependent electron transfer reaction which is essential to anaerobic energy metabolism. It has also been shown to have activity against influenza A virus in vitro. The mechanism appears to be by selectively blocking the maturation of the viral hemagglutinin at a stage preceding resistance to endoglycosidase H digestion. This impairs hemagglutinin intracellular trafficking and insertion of the protein into the host plasma membrane.
Function of Nitazoxanide?
Nitazoxanide is used to treat diarrhea in adults and children caused by the protozoa Giardia lamblia. Nitazoxanide is also used to treat diarrhea caused by the protozoa Cryptosporidium parvum. These conditions are also sometimes referred to as travelers' diarrhea. Nitazoxanide may also be used for purposes other than those listed in this medication guide.
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