High Quality Pharmaceutical Raw Material Powder Antispasmodic Agent Baclofen CAS 1134-47-0
Product Description
Product Name |
Baclofen |
CAS |
1134-47-0 |
Appearance |
white Powder |
Assay |
99% |
MOQ |
1KG |
Test Method |
HPLC |
Shelf Life |
24 months when properly stored |
Storage |
Keep in a cool, dry, dark location |
What Is Baclofen ?
Baclofen is a gamma-amino-butyric acid (GABA) derivative used as a skeletal muscle relaxant.Target: GABA ReceptorBaclofen, a lipophilic analog of gamma-aminobutyric acid, is clinically used to control spasticity. Baclofen pretreatment (3 mg/kg) not only prolonged the time taken for animals to reach a core body temperature of 40 degrees C (P < 0.001), but also reduced the percentage of rats attaining a core body temperature of 40 degrees C . Baclofen overdose may result in coma, apnea, autonomic disturbances, cardiac conduction abnormalities, and seizures. Levels obtained shortly after overdose correlate with length of mechanical ventilation
Function
1. Used for skeletal muscle spasm caused by multiple sclerosis.
2. Used for spasticity caused by infectious, degenerative, traumatic, tumor or unexplained spinal cord diseases, such as: spastic spinal palsy, amyotrophic lateral sclerosis, syringomyelitis, transverse myelitis, trauma Paraplegia or paralysis, spinal cord compression, spinal cord tumors, and motor neuron disease.
3. Used for brain-derived muscle spasm, such as: muscle spasm caused by cerebral palsy, pediatric cerebral palsy, stroke and cerebrovascular accident, brain tumor, degenerative encephalopathy, meningitis, and craniocerebral trauma.
4. It can also be used for urinary retention caused by external sphincter spasm.
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