Powder: | Yes |
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Customized: | Non-Customized |
Certification: | GMP, HSE, ISO 9001, USP, BP |
Suitable for: | Elderly, Children, Adult |
State: | Powder |
Purity: | >99% |
Samples: |
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Customization: |
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Product Name | Supply High Quality Proglumide CAS 6620-60-6 Anti-Ulcer |
Appearance | White powder |
Molecular formula | C18H26N2O4 |
Molecular weight | 334.41 |
Keywords | Proglumide, Material Proglumide ; Pure Proglumide |
Shelf Life | 24 months when properly stored |
Storage | Keep in a cool, dry, dark location |
What is Proglumide?
Proglumide (Milid) is a drug that inhibits gastrointestinal motility and reduces gastric secretions. It acts as a cholecystokinin antagonist, which blocks both the CCKA and CCKB subtypes. It was used mainly in the treatment of stomach ulcers, although it has now been largely replaced by newer drugs for this application.
Proglumide is a nonpeptide and orally active cholecystokinin (CCK)-A/B receptors antagonist. Proglumide selective blocks CCK's effects in the central nervous system (CNS). Proglumide has ability to inhibit gastric secretion and to protect the gastroduodenal mucosa. Proglumide also has antiepileptic and antioxidant activities.
1.It is an antagonist of gastrin receptor, which can protect gastric mucosa and promote ulcer healing.
2.For gastric and duodenal ulcer, gastritis (such as chronic superficial gastritis) and duodenal bulb inflammation.
3.Proglumide has been evaluated in the treatment of peptic ulcer disease, postoperative pain, Huntington's chorea, schizophrenia, gastric carcinoma, and colorectal carcinoma.
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