Factory Supply Powder 99% Purity Pharmaceutical Grade CAS 15663-27-1 Cisplatin Powder

• Powder: Yes
• Customized: Non-Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >99%
• Model NO.: HMJ-Cisplatin
• Color: Yellow
• Mf: Cl2h6n2PT
• Einecs: 239-733-8
• Test: HPLC
• MW: 300.05
• CAS: 15663-27-1
• Shelf Life: 2 Years
• Grade: Pharmaceutical Grade
• Transport Package: Ziplock Foil Bag. Drum
• Specification: 1kg Per Foil Bag, 10 Bags Per Carton, 25 Kg Per Dr
• Trademark: HMJ
• Origin: China
• Production Capacity: 200kg/Month

Product Description

Factory Supply Powder 99% Purity Pharmaceutical Grade CAS 15663-27-1 Cisplatin Powder

Product Description

 

Product Name	Factory Supply Powder 99% Purity Pharmaceutical Grade CAS 15663-27-1 Cisplatin Powder
Appearance	Yellow powder
Molecular formula	Cl2H6N2Pt
Molecular weight	300.05
Keywords	Powder Cisplatin  ,Price Cisplatin  ; Pure Cisplatin
Shelf Life	24 months when properly stored
Storage	Keep in a cool, dry, dark location

Function

What is Cisplatin 

This product is a heavy metal complex center at two price of platinum with two atoms and two ammoniamolecule, similar to the bifunctional alkylating agent, can inhibit the DNA replication process. The most sne DDP cells, high concentrations inhibit RNA and protein synthesis. The lack of effect of oxygen cells, into the human body can diffuse through the cell membrane charged. At present, the main site of DDP in DNA of the purine and pyrimidine bases. Effect: This product is a cell cycle non-specific drugs, has the cell toxicity, the process of DNA replication can inhibit cancer cells, and damage to the cell membrane structure, a broad-spectrum anticancer role.

Function of Cisplatin

Cisplatin is a potent platinum-based anti-neoplastic agent that is believed to form inter- and intrastrand DNA adducts which activate signaling pathways culminating in apoptosis. The compound has also been shown to induce apoptosis through caspase-3 activation and XIAP expression. Also shown to cause immunosuppression which is thought to be followed by an increase in the host immune response. Platinated DNA adducts also enhance poisoning of DNA topoisomerase I by camptothecin (sc-200871). Cisplatin was the first member of a class of anticancer drugs, which now include carboplatin (sc-202093) and oxaliplatin (sc-202270), that form DNA adducts resulting in apoptosis; however, these molecules also bind other biological molecules such as enzymes which might play a role in their mechanism of action.
 

Application

Cisplatin, cisplatinum, or cis-diamminedichloroplatinum(II)  is a platinum-based chemotherapydrug used to treat various types of cancers, including sarcomas, somecarcinomas (e.g. small cell lung cancer, and ovarian cancer), lymphomas, andgerm cell tumors.

It was the first member of a class of anti-cancer drugs which now also includes carboplatin and oxaliplatin. These platinum complexes react in vivo, binding to and causing crosslinking of DNA which ultimately triggers apoptosis (programmed cell death).

 

 

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